Plasma Cholesterol-Lowering Activity of Soybean Germ Phytosterols

Plasma LDL cholesterol lowering by plant phytosterols in a hamster model

Cardiovascular disease is still the main cause of death in the US. High plasma cholesterol, 51.9% of Americans have cholesterol levels of 200 mg/dl or higher and especially low-density lipoprotein (LDL) cholesterol, and high ratios of LDL to high-density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Plant stanol esters have been shown to be effective in reducing pla...

Lipid-lowering activity of Cow urine ark in guinea pigs fed with a high cholesterol diet

Objectives: Cow urine ark (CUA), known as “Amrita” as mentioned in Ayurveda, contains‎ anti-hyperglycemic and antioxidant effects. Therefore, we designed the present study to evaluate the lipid ‎lowering activity of CUA and its possible implication in metabolic syndrome.‎ Materials and Methods: Thirty guinea pigs of either sex were divided into five groups: Group 1 and 2 serving as a vehicle ‎a...

CHOLESTEROL LOWERING EFFECT OF RHEUM RIBS IN HYPERCHOLESTEROLEMIC RABBITS

The effects of ethanolic and aqueous extracts of Rheum ribs L. (RR) of the family polygonaceae was studied on serum cholesterol concentration in rabbits. To induce hypercholesterolemia, 0.5 g/kg/day of pure cholesterol powder was given orally to each rabbit for two weeks then cholesterol was halved and each group of animals was treated with a different regimen for another two weeks. Both t...

From Soybean Phytosterols to Steroid Hormones

Role of phytosterols in lipid-lowering: current perspectives.

The cholesterol-lowering effect of plant sterols was first discovered in the early 1950s. However, it is only recently that plant sterols have become clinically important, when advances in food-technology have made it possible to combine sterols with a variety of food products including margarines, yogurts, fruit juices and cereal bars. We review the clinical trial evidence of lipid-lowering ef...